Dosages of commonly used sedatives/analgesics/neuromuscular blockers

 

(Prepared by Dr Veena V Nair, Dr Abhishek Kulkarni and Dr Banani Poddar)

 

(*all doses are IV unless mentioned otherwise)

 

Drug

Bolus (mg/kg)*

Infusion

Midazolam

0.05 - 0.1 mg/kg

IM: same as IV

PO: 0.5 mg/kg

Nasal: 0.2, rpt in 10 min

1 - 7 μg/kg/min

Diazepam

0.1   - 0.4 mg/kg

PO: 0.04 0.2 mg/kg

PR: same as IV

1 - 6 μg/kg/min

Morphine

0.05 0.1

10 40 μg/kg/hr

Fentanyl

1 - 2 μg/kg

1 - 4 μg/kg/hr

Propofol

0.5 - 1.0 mg/kg

25 - 100 μg/kg/min

Vecuronium

0.1 mg/kg

0.05 - 0.1 mg/kg/hr.

Rocuronium

0.6-1.2 mg/kg

5-15 μg/kg/min

Paracetamol

10-15 mg/kg, 6 hrly

PO/PR: 15

 

Ketamine

0.5-2 mg/kg

Not recommended

Triclorofos

PO: 25 50 mg/kg

 

 

(*all doses are IV unless mentioned otherwise)