Department of Transfusion Medicine
Laboratory Services
    Specialized Services

    Therapeutic Plasma Exchange (TPE)
    Gamma Irradiation
    Donor Call Back for Hepatitis
     

    Therapeutic Plasma Exchange (TPE)
    The department is actively collaborating with clinical departments, in particular Neurology, Nephrology and Immunology, for therapeutic plasma exchange in various disorders, such as Myasthenia Gravis, Gullain Barre Syndrome, Chronic Inflammatory Demyelinating Polyneuropathy, TTP, HUS etc. The procedure is performed using automatic cell separators.  

    Gamma Irradiation
    Transfusion-associated graft-versus-host disease (TA-GvHD) is a rare but highly lethal complication resulting from engraftment, proliferation and immunologic attack of recipient tissues by transfused donor T lymphocytes. To prevent this dreaded complication, all cellular blood components should be gamma irradiated.  In the department of Transfusion Medicine at SGPGI, blood is irradiated using Cesium-137 in a self-contained gamma irradiator. A dose of 2500 rad is delivered to eliminate all lymphocytes from cellular components. Presently, the department is irradiating all cellular components required for BMT recipients, intrauterine transfusions, exchange transfusions in neonates, and for patients with Hodgkin’s disease and congenital immunodeficiency syndromes. 
     

    Donor Call Back for Hepatitis
    Every unit of donated blood is screened for HBsAg and anti-HCV by ELISA. Reactive samples are retested and those testing positive again are considered as confirmed positive. The respective blood donors are notified about their hepatitis tests results and are requested to report to the Blood Center. A blood sample is withdrawn and detailed questionnaire is filled up. The donor is then referred to the Department of Gastroenterology at the Institute. All further testing is done free of cost.
     

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